This blog is to share the latest research and development of acupuncture and raise the awareness of alternative treatments for your conditions, and is for information only.

Wednesday, 18 November 2015

Acupuncture improved the clinical pregnancy rate during IVF

Electroacupuncture stimulation enhanced the clinical pregnancy rate in patients with decreased ovarian reserve during IVF and embryo transfer cycles, according to a clinical study published in the Journal of Obstetrics and Gynaecological Research.

Although IVF is commonly used to treat infertility the success rate is not satisfactory. As many women, undergoing IVF treatment, had a decreased or diminished ovarian reserve. Ovarian reserve is a capacity of the ovary to provide egg cells that are capable of fertilization, resulting in a healthy and successful pregnancy. So improve ovarian reserve is very important to enhance pregnancy rate during IVF.

Recently a group of researchers in China conducted a clinical study to assess the effect of acupuncture on pregnancy rate in patients with decreased ovarian reserve during IVF and embryo transfer cycles. Two-hundred-forty patients were randomly allocated into acupuncture group, placebo group, artificial endometrial cycle treatment group and control group.

Electroacupuncture was given to following acupoints: RN3, RN4, DU3, DU4, SP6, ST25, BL23 and EX-CA1; for 30min, once a day during ovulation cycle until the day of egg retrieval. Outcome measures include pregnancy-related perimeters such as, AFC, basal estradiol (E2) level, basal FSH level, basal luteinizing hormone (LH) level, AMH level, FSH/LH ratio, ovarian artery resistance index (RI), ovarian artery pulsatility index (PI), and systolic/diastolic flow velocity ratio (S/D).

At the end of treatment, if was found that the number of egg cells retrieved and average number of embryos transferred were higher in the acupuncture group and artificial endometrial cycle group than those of control groups. Antral follicle count and anti-Müllerian hormone levels were increased, whereas the estradiol level, follicle-stimulating hormone level, and follicle-stimulating hormone/luteinizing hormone ratio were significantly decreased following acupuncture and artificial endometrial group compared with control groups.

The study showed that electroacupuncture enhanced pregnancy rate in patients with decreased ovarian reserve during IVF and embryo transfer cycle.

Reference

Zheng Y, et al., Effects of transcutaneous electrical acupoint stimulation on ovarian reserve of patients with diminished ovarian reserve in in vitro fertilization and embryo transfer cycles. J Obstet Gynaecol Res. 2015 Oct 12. doi: 10.1111/jog.12810.  http://www.ncbi.nlm.nih.gov/pubmed/26455718

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