This blog is to share the latest research and development of acupuncture and raise the awareness of alternative treatments for your conditions, and is for information only.

Wednesday 17 July 2019

Acupuncture is more effective than drug treatment in relieving gout symptoms


Acupuncture therapy is shown to be more effective than conventional medication for gouty arthritis in a clinical study which was recently reported in the journal of Chinese Medicine Report.

Gouty arthritis is caused by a build-up of a substance called uric acid in the blood, resulting in the formation of small crystal deposits in and around the joints. It's estimated that 1-2% people are affected by gout in the developed countries. Men over 30 and women after the menopause are more likely affected. Gout is seen more common in men than women. People with obesity, diabetes mellitus, hypertension, hyperlipidaemia, and chronic renal disease are prone to developing gout. Conventional medications help relief pain and reduce hyperuricaemia. However, long term use of such medications could cause many adverse effects. Acupuncture has been used to effectively treat gout for a long time.

A clinical study has been recently conducted to assess the efficacy of acupuncture on the gout in comparison with conventional medication. A total of 92 patients with acute gouty arthritis were recruited and randomly allocated to either acupuncture group (n=46) or the medication group (n=46). In acupuncture group the filiform needles were applied on the following primary acupoints bilaterally: Zusanli (ST36), Sanyinjiao (SP6), Yinlingquan (SP9), Quchi (LI11) and ashi points for 30 mins a day for 5 consecutive days, then 2-day break followed by another 5-day consecutive treatment. In addition some secondary acupoints were applied according to patient’s affected joints. In medication group, patients were given indomethacin enteric-coated 75 mg tablets twice daily for 10 days. The study’s outcome measures included a VAS (visual analog scale) for pain, serum levels of uric acid and pro-inflammatory chemokine interleukin 8 (IL-8), and monitored at the beginning and end of the study.

Results showed that mean VAS scores were 4.26 in the medication group and 4.31 in the acupuncture group before treatment. The scores fell to 1.61 and 0.78 respectively at the end of treatment, indicating significant decrease in pain in both groups. However, pain reduction in the acupuncture group is greater (p<0.05) than medication group. Mean uric acid levels were 519.92 µmol/L in the medication group and 525.06 µmol/L in the acupuncture group respectively before treatment. Uric acid levels fell to 437.28 µmol/L and 426.53 µmol/L respectively following treatment. Mean IL-8 levels were 38.24 µg/L in the medication group and 38.81 µg/L in the acupuncture group before treatment, then, IL-8 levels fell to 26.23 µg/L and 26.04 µg/L respectively after treatment. The clinical symptoms e.g. mean mobility scores were 1.57, redness and swelling were 1.92 and joint function was 1.63 in medication group before treatment. In acupuncture group corresponding scores were 1.59, 1.99, and 1.65 respectively before treatment. At the end of treatment, these scores fell to 0.89, 1.25, and 0.92 in the medication group and 0.56, 0.72, and 0.72 in the acupuncture group. Although both groups demonstrated improvements in clinical conditions, symptom relief was significantly greater in the acupuncture group (p<0.05) than that of medication group.

Present study demonstrated that acupuncture markedly improved clinical symptoms and reduced both serum uric acid and IL-8 levels in patients with gouty arthritis and offers an effective and well-tolerated alternative treatment for gout.

Reference:

Z Chen (2019) “Clinical Observation on Acupuncture Treatment of Acute Gout Arthritis” Chinese Medicine Research Vol.16(3) pp.75-78.