This blog is to share the latest research and development of acupuncture and raise the awareness of alternative treatments for your conditions, and is for information only.

Monday, 16 June 2014

Mechanisms underlying versatile functions of acupoint Zusanli (ST36)

Acupoint Zusanli (ST36), located on the stomach meridian, is one of the most frequently used acupoints. It is believed to be one of the most important acupoints to tonify qi and blood and promote well-being according to the traditional Chinese medicine theory. Acupoint ST36 is used, in combination with other acupoints, to treat visceral conditions such as vomiting, abdominal distension and visceral pain, constipation, and hypertension, fatigue, depression, generalized pain, anxiety, palpitation, infection and many other things.  

The interesting in the mechanisms underlying the versatile functions of acupoint ST36 has attracted many scientific studies. It has been reported that stimulation at acupoint ST36 induces vagus nerve activity, on the one hand, leading to production of dopamine in the adrenal medullar, suppress the systemic inflammation resulting in controlling of sepsis; on the other hand, elevated vagus nerve activity increased superior mesenteric artery blood flow volume. Further brain imaging studies reported that stimulation ST36 acupoint can specifically induce the neural responses in pain-inhibiting areas in the brain. Those studies suggest stimulation acupoint ST36 rebalanced sympathetic and parasympathetic systems and explains in partial how stimulation the ST36 acupoint exerts its therapeutic effects on the conditions mentioned above.

The studies also showed that effects elicited by stimulation ST36 are acupoint specific as stimulation the non-specific points or other acupoints do not produce the same results.

Reference:
Kaneko S et al., Heart Rate Variability and Hemodynamic Change in the Superior Mesenteric Artery by Acupuncture Stimulation of Lower Limb Points: A Randomized Crossover Trial. Evid Based Complement Alternat Med, Volume 2013, Article ID 315982.   http://www.hindawi.com/journals/ecam/2013/315982/

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